Housekeeping Genes. Housekeeping genes are typically constitutive genes that are required for the maintenance of basal cellular functions that are essential for the existence of a cell, regardless of its specific role in the tissue or organism Housekeeping genes are commonly described as "essential for cellular existence regardless of their specific function in the tissue or organism", and.
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Biochemical studies on transcription initiation of the housekeeping gene promoters have been difficult, partly due to the less-characterized promoter motifs. Housekeeping genes are commonly described as "essential for cellular existence regardless of their specific function in the tissue or organism", and.
Housekeeping genes are commonly described as "essential for cellular existence regardless of their specific function in the tissue or organism", and "stably expressed irrespective of tissue type, developme. Thus, they are expected to be expressed in all cells of an organism under normal conditions, irrespective of tissue type, developmental stage, cell cycle state, or external signal Introduction Housekeeping genes are often defined as being stably expressed in all cells and conditions [1], essential [2], belong to cellular maintenance pathways [1,3-6] and be conserved [7,8]
. Housekeeping genes account for majority of the active genes in the genome, and their expression is obviously vital to survival Introduction Housekeeping genes are often defined as being stably expressed in all cells and conditions [1], essential [2], belong to cellular maintenance pathways [1,3-6] and be conserved [7,8]
. Housekeeping genes are commonly described as "essential for cellular existence regardless of their specific function in the tissue or organism", and "stably expressed irrespective of tissue type, developme. The housekeeping gene expression levels are fine-tuned to meet the metabolic requirements in various tissues